In the last 20 years, spurred by governmental incentives (American Recovery and Reinvestment) the digitization of devices and widespread adoption of electronic record keeping systems has transformed medical care for better (and some would argue for worse). Medical care and research has spawned the development of vast troves of digitized clinical and research data. Medical information flows through countless visible and invisible conduits, and has become the new oil, coveted by large companies, research initiatives and governments. This talk will describe the digitization of medicine, the players, the intended and unintended consequences and the potential benefits of AI and precision medicine. It will offer a perspective on what has gone right, what wrong and what entities like Princeton Precision Health can bring to the table.